Malonyl-CoA decarboxylase, mitochondrial · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O95822. Use UniProt O95822 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95822 as the stable identity anchor, then attach disease evidence before program review.
Malonyl-CoA decarboxylase, mitochondrial
Review this target as Malonyl-CoA decarboxylase, mitochondrial, mapped to UniProt O95822. Sequence length is 493 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Malonyl-CoA decarboxylase, mitochondrial as ChEMBL target CHEMBL4698, mapped to UniProt O95822. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Malonyl-CoA decarboxylase, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95822 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Malonyl-CoA decarboxylase, mitochondrial |
| UniProt Accession | O95822 |
| Component Type | Protein |
| Sequence Length | 493 aa |
Malonyl-CoA decarboxylase, mitochondrial
Review this target as Malonyl-CoA decarboxylase, mitochondrial, mapped to UniProt O95822. Sequence length is 493 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL205986 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL380487 | 9.54 | IC50 | 0.29 | Preclinical |
| CHEMBL1258253 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL1258254 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL205506 | 9.07 | IC50 | 0.85 | Preclinical |
| CHEMBL1257549 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL1258367 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL204287 | 9.01 | IC50 | 0.98 | Preclinical |
| CHEMBL202688 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1257909 | 8.96 | IC50 | 1.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 275 | 6.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 0 | — |