Dopamine beta-hydroxylase · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P15101. Use UniProt P15101 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15101 as the stable identity anchor, then attach disease evidence before program review.
Dopamine beta-hydroxylase
Review this target as Dopamine beta-hydroxylase, mapped to UniProt P15101. Sequence length is 610 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dopamine beta-hydroxylase as ChEMBL target CHEMBL4702, mapped to UniProt P15101. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Dopamine beta-hydroxylase is the right protein anchor across sources, using UniProt P15101 as the stable mapping.
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| Preferred Name | Dopamine beta-hydroxylase |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P15101 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dopamine beta-hydroxylase |
| UniProt Accession | P15101 |
| Component Type | Protein |
| Sequence Length | 610 aa |
Dopamine beta-hydroxylase
Review this target as Dopamine beta-hydroxylase, mapped to UniProt P15101. Sequence length is 610 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL433493 | 8.24 | Ki | 5.7 | Preclinical |
| CHEMBL351873 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL4764135 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL278068 | 7.39 | Ki | 41.0 | Preclinical |
| CHEMBL24510 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL164747 | 7.26 | Ki | 54.9 | Preclinical |
| CHEMBL433493 | 7.13 | IC50 | 74.0 | Preclinical |
| CHEMBL275322 | 6.94 | IC50 | 114.4 | Preclinical |
| CHEMBL54434 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL24510 | 6.83 | Ki | 149.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 94 | 100 | 5.3 |
| tissue-based format | 4 | 11 | — |