Receptor-histidine kinase AgrC · SINGLE PROTEIN · Staphylococcus aureus
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As of 2026-09-14Protein identity stays anchored to UniProt O07911. Use UniProt O07911 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O07911 as the stable identity anchor, then attach disease evidence before program review.
AgrC
Review this target as Receptor-histidine kinase AgrC, mapped to UniProt O07911. ChEMBL maps the protein component as AgrC. Sequence length is 430 aa.
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This review treats Receptor-histidine kinase AgrC as ChEMBL target CHEMBL4726, mapped to UniProt O07911. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Receptor-histidine kinase AgrC |
| Target Type | SINGLE PROTEIN |
| Organism | Staphylococcus aureus |
| UniProt | O07911 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | AgrC |
| UniProt Accession | O07911 |
| Component Type | Protein |
| Sequence Length | 430 aa |
AgrC
Review this target as Receptor-histidine kinase AgrC, mapped to UniProt O07911. ChEMBL maps the protein component as AgrC. Sequence length is 430 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL182114 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL359961 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL362838 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL182783 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL426697 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL2371770 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL3289785 | 8.54 | IC50 | 2.9 | Preclinical |
| CHEMBL2337554 | 8.51 | IC50 | 3.1 | Preclinical |
| CHEMBL182783 | 8.44 | EC50 | 3.6 | Preclinical |
| CHEMBL360749 | 8.22 | IC50 | 6.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 12 | 7.8 |
| assay format | 2 | 8 | 5.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 4 | 7.6 |