DNA excision repair protein ERCC-5 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P28715. Use UniProt P28715 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28715 as the stable identity anchor, then attach disease evidence before program review.
DNA excision repair protein ERCC-5
Review this target as DNA excision repair protein ERCC-5, mapped to UniProt P28715. Sequence length is 1186 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA excision repair protein ERCC-5 as ChEMBL target CHEMBL4736, mapped to UniProt P28715. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | DNA excision repair protein ERCC-5 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P28715 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA excision repair protein ERCC-5 |
| UniProt Accession | P28715 |
| Component Type | Protein |
| Sequence Length | 1186 aa |
DNA excision repair protein ERCC-5
Review this target as DNA excision repair protein ERCC-5, mapped to UniProt P28715. Sequence length is 1186 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL361962 | 10.64 | IC50 | 0.023 | Preclinical |
| CHEMBL361011 | 10.55 | IC50 | 0.028 | Preclinical |
| CHEMBL183133 | 10.21 | IC50 | 0.061 | Preclinical |
| CHEMBL359533 | 10.21 | IC50 | 0.062 | Preclinical |
| CHEMBL361350 | 10.0 | IC50 | 0.101 | Preclinical |
| CHEMBL182381 | 9.89 | IC50 | 0.128 | Preclinical |
| CHEMBL364591 | 9.87 | IC50 | 0.136 | Preclinical |
| CHEMBL183792 | 9.84 | IC50 | 0.145 | Preclinical |
| CHEMBL183852 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL362842 | 9.8 | IC50 | 0.157 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 120 | 6.2 |