Potassium channel subfamily T member 1 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q5JUK3. Use UniProt Q5JUK3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5JUK3 as the stable identity anchor, then attach disease evidence before program review.
Potassium channel subfamily T member 1
Review this target as Potassium channel subfamily T member 1, mapped to UniProt Q5JUK3. Sequence length is 1230 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium channel subfamily T member 1 as ChEMBL target CHEMBL4739688, mapped to UniProt Q5JUK3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Potassium channel subfamily T member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q5JUK3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium channel subfamily T member 1 |
| UniProt Accession | Q5JUK3 |
| Component Type | Protein |
| Sequence Length | 1230 aa |
Potassium channel subfamily T member 1
Review this target as Potassium channel subfamily T member 1, mapped to UniProt Q5JUK3. Sequence length is 1230 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4763955 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL4788669 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL4741793 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL4754084 | 7.21 | IC50 | 61.0 | Preclinical |
| CHEMBL5558979 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL4783741 | 6.87 | IC50 | 136.0 | Preclinical |
| CHEMBL4786255 | 6.78 | IC50 | 165.0 | Preclinical |
| CHEMBL4793291 | 6.78 | IC50 | 167.0 | Preclinical |
| CHEMBL4793279 | 6.71 | IC50 | 195.0 | Preclinical |
| CHEMBL2398613 | 6.7 | IC50 | 200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 19 | 62 | 5.8 |
| single protein format | 1 | 0 | — |