Use UniProt Q8NBS9 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4739698 Target Snapshot
Thioredoxin domain-containing protein 5 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8NBS9. Use UniProt Q8NBS9 as the stable identity anchor, then attach disease evidence before program review.
Thioredoxin domain-containing protein 5
Review this target as Thioredoxin domain-containing protein 5, mapped to UniProt Q8NBS9. Sequence length is 432 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Thioredoxin domain-containing protein 5 as ChEMBL target CHEMBL4739698, mapped to UniProt Q8NBS9. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Thioredoxin domain-containing protein 5 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8NBS9 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thioredoxin domain-containing protein 5 |
| UniProt Accession | Q8NBS9 |
| Component Type | Protein |
| Sequence Length | 432 aa |
Thioredoxin domain-containing protein 5
How to read this target
Review this target as Thioredoxin domain-containing protein 5, mapped to UniProt Q8NBS9. Sequence length is 432 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 6.3 | Kd | 496.2 | Preclinical |
| CHEMBL4751979 | 4.92 | IC50 | 12100.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 2 | 5.6 |