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Target Snapshot

CHEMBL4739842 Target Snapshot

Formyl peptide receptor 2 · SINGLE PROTEIN · Mus musculus

10Compounds
5Assays
0Approved Drugs
13.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt O88536. Use UniProt O88536 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt O88536 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Formyl peptide receptor 2 as ChEMBL target CHEMBL4739842, mapped to UniProt O88536. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Formyl peptide receptor 2
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL4739842
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
O88536
Formyl peptide receptor 2
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Formyl peptide receptor 2 is the right protein anchor across sources, using UniProt O88536 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelFormyl peptide receptor 2
UniProt AccessionO88536
Component TypeProtein
Sequence Length351 aa

Formyl peptide receptor 2

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Formyl peptide receptor 2, mapped to UniProt O88536. Sequence length is 351 aa.

Mapped IDO88536
Review nameFormyl peptide receptor 2
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase I
Assay Mix

Activity Type Distribution

EC5013.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4784510 9.3 EC50 0.5 Preclinical
CHEMBL4790836 9.2 EC50 0.63 Preclinical
CHEMBL4760897 8.85 EC50 1.4 Preclinical
CHEMBL4781596 8.82 EC50 1.5 Preclinical
CHEMBL4762030 8.07 EC50 8.5 Preclinical
CHEMBL5556377 7.82 EC50 15.0 Preclinical
CHEMBL377226 7.3 EC50 50.0 Preclinical
CHEMBL5563384 6.55 EC50 280.0 Preclinical
CHEMBL379761 6.05 EC50 890.0 Preclinical
CHEMBL5560735 6.04 EC50 910.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
3
6.0
1
6.5
1
7.0
1
7.5
2
8.0
2
8.5
2
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

5
Total Assays
10
Tested Compounds
1
Assay Types
Binding — 5 assays, 10 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 6 8.3
single protein format 1 4 6.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine