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Target Snapshot

CHEMBL4739859 Target Snapshot

Relaxin receptor 1 · SINGLE PROTEIN · Rattus norvegicus

13Compounds
13Assays
0Approved Drugs
9.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q6R6I6. Use UniProt Q6R6I6 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q6R6I6 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Relaxin receptor 1 as ChEMBL target CHEMBL4739859, mapped to UniProt Q6R6I6. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Relaxin receptor 1
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL4739859
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q6R6I6
Relaxin receptor 1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Relaxin receptor 1 is the right protein anchor across sources, using UniProt Q6R6I6 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelRelaxin receptor 1
UniProt AccessionQ6R6I6
Component TypeProtein
Sequence Length758 aa

Relaxin receptor 1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Relaxin receptor 1, mapped to UniProt Q6R6I6. Sequence length is 758 aa.

Mapped IDQ6R6I6
Review nameRelaxin receptor 1
OrganismRattus norvegicus
Assay Mix

Activity Type Distribution

EC509.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4754949 9.3 EC50 0.5 Preclinical
CHEMBL4793799 9.05 EC50 0.9 Preclinical
CHEMBL4781560 8.28 EC50 5.3 Preclinical
CHEMBL5194101 6.7 EC50 199.53 Preclinical
CHEMBL5559571 5.31 EC50 4897.79 Preclinical
CHEMBL5552957 5.1 EC50 7943.28 Preclinical
CHEMBL5555416 5.0 EC50 10000.0 Preclinical
CHEMBL5560417 4.98 EC50 10471.29 Preclinical
CHEMBL5550064 4.8 EC50 15848.93 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
0
5.5
0
6.0
1
6.5
0
7.0
0
7.5
1
8.0
0
8.5
2
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

13
Total Assays
6
Tested Compounds
2
Assay Types
Functional — 10 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 6 6 5.3
organism-based format 4 0
Binding — 3 assays, 3 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 3 3 8.9

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine