C3a anaphylatoxin chemotactic receptor · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q16581. Use UniProt Q16581 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q16581 as the stable identity anchor, then attach disease evidence before program review.
C3a anaphylatoxin chemotactic receptor
Review this target as C3a anaphylatoxin chemotactic receptor, mapped to UniProt Q16581. Sequence length is 482 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats C3a anaphylatoxin chemotactic receptor as ChEMBL target CHEMBL4761, mapped to UniProt Q16581. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | C3a anaphylatoxin chemotactic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q16581 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | C3a anaphylatoxin chemotactic receptor |
| UniProt Accession | Q16581 |
| Component Type | Protein |
| Sequence Length | 482 aa |
C3a anaphylatoxin chemotactic receptor
Review this target as C3a anaphylatoxin chemotactic receptor, mapped to UniProt Q16581. Sequence length is 482 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1170042 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL3342676 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL2064013 | 8.73 | IC50 | 1.862 | Preclinical |
| CHEMBL1170024 | 8.7 | IC50 | 1.995 | Preclinical |
| CHEMBL4470864 | 8.7 | IC50 | 1.995 | Preclinical |
| CHEMBL4445758 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3342678 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4559976 | 8.4 | IC50 | 3.981 | Preclinical |
| CHEMBL4576800 | 8.4 | IC50 | 3.981 | Preclinical |
| CHEMBL2064017 | 8.34 | IC50 | 4.571 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 38 | 138 | 6.3 |
| assay format | 7 | 7 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 85 | 6.5 |
| single protein format | 10 | 48 | 6.7 |
| assay format | 6 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 4 | 6.8 |