Acetylcholinesterase · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P23795. Use UniProt P23795 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23795 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholinesterase
Review this target as Acetylcholinesterase, mapped to UniProt P23795. Sequence length is 613 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetylcholinesterase as ChEMBL target CHEMBL4768, mapped to UniProt P23795. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetylcholinesterase |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P23795 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholinesterase |
| UniProt Accession | P23795 |
| Component Type | Protein |
| Sequence Length | 613 aa |
Acetylcholinesterase
Review this target as Acetylcholinesterase, mapped to UniProt P23795. Sequence length is 613 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL225567 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL140476 | 10.61 | IC50 | 0.0245 | Preclinical |
| CHEMBL225198 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL338755 | 10.22 | Ki | 0.06 | Preclinical |
| CHEMBL208599 | 10.17 | IC50 | 0.0674 | Preclinical |
| CHEMBL3216655 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL1652 | 9.92 | IC50 | 0.12 | Approved |
| CHEMBL477141 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL223443 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL381499 | 9.7 | IC50 | 0.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 81 | 296 | 6.6 |
| assay format | 19 | 124 | 7.2 |
| cell-based format | 14 | 62 | 7.2 |
| tissue-based format | 3 | 7 | 6.0 |