ATP-sensitive inward rectifier potassium channel 8 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14ATP-sensitive inward rectifier potassium channel 8 shows approved-linked disease relevance led by hyperinsulinism. 5 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt Q15842. Start with hyperinsulinism, then reuse UniProt Q15842 as the stable protein anchor across project notes and exports.
Start with hyperinsulinism, then reuse UniProt Q15842 as the stable protein anchor across project notes and exports.
ATP-sensitive inward rectifier potassium channel 8 shows approved-linked disease relevance led by hyperinsulinism. 5 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with hyperinsulinism because it currently carries approved-linked support. Linked drugs include DIAZOXIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyATP-sensitive inward rectifier potassium channel 8
Review this target as ATP-sensitive inward rectifier potassium channel 8, mapped to UniProt Q15842. Sequence length is 424 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ATP-sensitive inward rectifier potassium channel 8 as ChEMBL target CHEMBL4770, mapped to UniProt Q15842. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether ATP-sensitive inward rectifier potassium channel 8 is the right protein anchor across sources, using UniProt Q15842 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why hyperinsulinism is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | ATP-sensitive inward rectifier potassium channel 8 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15842 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATP-sensitive inward rectifier potassium channel 8 |
| UniProt Accession | Q15842 |
| Component Type | Protein |
| Sequence Length | 424 aa |
ATP-sensitive inward rectifier potassium channel 8
Review this target as ATP-sensitive inward rectifier potassium channel 8, mapped to UniProt Q15842. Sequence length is 424 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
ATP-sensitive inward rectifier potassium channel 8 shows approved-linked disease relevance led by hyperinsulinism. 5 more disease programs remain visible in the same review block.
Start review with hyperinsulinism because it currently carries approved-linked support. Linked drugs include DIAZOXIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.