M-phase inducer phosphatase 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P30305. Use UniProt P30305 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30305 as the stable identity anchor, then attach disease evidence before program review.
M-phase inducer phosphatase 2
Review this target as M-phase inducer phosphatase 2, mapped to UniProt P30305. Sequence length is 580 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats M-phase inducer phosphatase 2 as ChEMBL target CHEMBL4804, mapped to UniProt P30305. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | M-phase inducer phosphatase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P30305 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | M-phase inducer phosphatase 2 |
| UniProt Accession | P30305 |
| Component Type | Protein |
| Sequence Length | 580 aa |
M-phase inducer phosphatase 2
Review this target as M-phase inducer phosphatase 2, mapped to UniProt P30305. Sequence length is 580 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5271462 | 7.28 | IC50 | 53.0 | Preclinical |
| CHEMBL5288122 | 7.28 | IC50 | 53.0 | Preclinical |
| CHEMBL476648 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL1481974 | 7.1 | Ki | 80.0 | Preclinical |
| CHEMBL337173 | 7.02 | Ki | 95.0 | Preclinical |
| CHEMBL1481974 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL429095 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL1095726 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL200117 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL1097720 | 6.8 | IC50 | 160.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 111 | 434 | 5.1 |
| assay format | 35 | 101 | 5.5 |
| cell-based format | 20 | 48 | 5.0 |