Use UniProt P05363 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4815 Target Snapshot
Substance-K receptor · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P05363. Use UniProt P05363 as the stable identity anchor, then attach disease evidence before program review.
Substance-K receptor
Review this target as Substance-K receptor, mapped to UniProt P05363. Sequence length is 384 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Substance-K receptor as ChEMBL target CHEMBL4815, mapped to UniProt P05363. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Substance-K receptor is the right protein anchor across sources, using UniProt P05363 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Substance-K receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P05363 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Substance-K receptor |
| UniProt Accession | P05363 |
| Component Type | Protein |
| Sequence Length | 384 aa |
Substance-K receptor
How to read this target
Review this target as Substance-K receptor, mapped to UniProt P05363. Sequence length is 384 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL308148 | 9.3 | Ki | 0.5 | Clinical |
| CHEMBL71397 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL290364 | 5.55 | IC50 | 2790.0 | Preclinical |
| CHEMBL43912 | 5.35 | IC50 | 4500.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 6 assays, 4 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 4 | 7.3 |