Prostaglandin F2-alpha receptor · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P37289. Use UniProt P37289 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P37289 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin F2-alpha receptor
Review this target as Prostaglandin F2-alpha receptor, mapped to UniProt P37289. Sequence length is 362 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin F2-alpha receptor as ChEMBL target CHEMBL4820, mapped to UniProt P37289. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin F2-alpha receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P37289 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin F2-alpha receptor |
| UniProt Accession | P37289 |
| Component Type | Protein |
| Sequence Length | 362 aa |
Prostaglandin F2-alpha receptor
Review this target as Prostaglandin F2-alpha receptor, mapped to UniProt P37289. Sequence length is 362 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1910324 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL185484 | 7.28 | Ki | 52.0 | Preclinical |
| CHEMBL491667 | 7.14 | Ki | 72.0 | Preclinical |
| CHEMBL491475 | 7.06 | Ki | 87.0 | Preclinical |
| CHEMBL364375 | 7.04 | Ki | 92.0 | Preclinical |
| CHEMBL1050 | 7.01 | Ki | 98.0 | Preclinical |
| CHEMBL523143 | 6.92 | Ki | 120.0 | Preclinical |
| CHEMBL521964 | 6.89 | Ki | 130.0 | Preclinical |
| CHEMBL815 | 6.89 | Ki | 129.0 | Approved |
| CHEMBL489109 | 6.85 | Ki | 140.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 10 | 5.5 |
| cell membrane format | 1 | 8 | 6.9 |
| single protein format | 1 | 15 | 6.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 1 | 7.9 |