Transcription initiation factor IIA subunit 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P52655. Use UniProt P52655 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P52655 as the stable identity anchor, then attach disease evidence before program review.
Transcription initiation factor IIA subunit 1
Review this target as Transcription initiation factor IIA subunit 1, mapped to UniProt P52655. Sequence length is 376 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transcription initiation factor IIA subunit 1 as ChEMBL target CHEMBL4832, mapped to UniProt P52655. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Transcription initiation factor IIA subunit 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P52655 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcription initiation factor IIA subunit 1 |
| UniProt Accession | P52655 |
| Component Type | Protein |
| Sequence Length | 376 aa |
Transcription initiation factor IIA subunit 1
Review this target as Transcription initiation factor IIA subunit 1, mapped to UniProt P52655. Sequence length is 376 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3660186 | 6.62 | Ki | 240.0 | Preclinical |
| CHEMBL3660173 | 6.1 | Ki | 800.0 | Preclinical |
| CHEMBL3660190 | 6.04 | Ki | 920.0 | Preclinical |
| CHEMBL3660191 | 5.92 | Ki | 1200.0 | Preclinical |
| CHEMBL3660187 | 5.77 | Ki | 1700.0 | Preclinical |
| CHEMBL3660189 | 5.44 | Ki | 3600.0 | Preclinical |
| CHEMBL3660176 | 5.42 | Ki | 3800.0 | Preclinical |
| CHEMBL3660179 | 5.41 | Ki | 3900.0 | Preclinical |
| CHEMBL3660177 | 5.38 | Ki | 4200.0 | Preclinical |
| CHEMBL3660171 | 5.36 | Ki | 4400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 22 | 5.4 |