Reduced folate transporter · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P41440. Use UniProt P41440 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P41440 as the stable identity anchor, then attach disease evidence before program review.
Reduced folate transporter
Review this target as Reduced folate transporter, mapped to UniProt P41440. Sequence length is 591 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Reduced folate transporter as ChEMBL target CHEMBL4833, mapped to UniProt P41440. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Reduced folate transporter is the right protein anchor across sources, using UniProt P41440 as the stable mapping.
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| Preferred Name | Reduced folate transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P41440 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Reduced folate transporter |
| UniProt Accession | P41440 |
| Component Type | Protein |
| Sequence Length | 591 aa |
Reduced folate transporter
Review this target as Reduced folate transporter, mapped to UniProt P41440. Sequence length is 591 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1201746 | 9.16 | IC50 | 0.69 | Approved |
| CHEMBL225071 | 8.2 | IC50 | 6.3 | Approved |
| CHEMBL34259 | 7.92 | IC50 | 12.0 | Approved |
| CHEMBL4445651 | 7.7 | IC50 | 20.1 | Preclinical |
| CHEMBL225072 | 7.62 | IC50 | 23.8 | Approved |
| CHEMBL3409335 | 7.42 | IC50 | 38.3 | Preclinical |
| CHEMBL3628345 | 7.27 | IC50 | 54.0 | Preclinical |
| CHEMBL3407519 | 7.22 | IC50 | 59.8 | Preclinical |
| CHEMBL4538151 | 7.21 | IC50 | 62.0 | Preclinical |
| CHEMBL3628344 | 7.2 | IC50 | 62.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 17 | 26 | 7.0 |
| single protein format | 1 | 1 | 5.5 |