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Target Snapshot

CHEMBL4845623 Target Snapshot

HOXA9 DNA binding site · NUCLEIC-ACID · Homo sapiens

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39Compounds
24Assays
0Approved Drugs
6.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats HOXA9 DNA binding site as ChEMBL target CHEMBL4845623. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
HOXA9 DNA binding site
NUCLEIC-ACID · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL4845623
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether HOXA9 DNA binding site still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameHOXA9 DNA binding site
Target TypeNUCLEIC-ACID
OrganismHomo sapiens
ChEMBL ↗ NCBI Nucleotide ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHOXA9 DNA binding site
UniProt AccessionN/A

HOXA9 DNA binding site

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as HOXA9 DNA binding site.

Review nameHOXA9 DNA binding site
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

KD6.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1234147 8.6 Kd 2.5 Preclinical
CHEMBL1232046 8.57 Kd 2.7 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
1
5.5
1
6.0
0
6.5
0
7.0
0
7.5
2
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

24
Total Assays
2
Tested Compounds
1
Assay Types
Binding — 24 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
nucleic acid format 16 2 7.7
subcellular format 6 0 —
cell-based format 2 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine