Receptor-type tyrosine-protein phosphatase epsilon · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P23469. Use UniProt P23469 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23469 as the stable identity anchor, then attach disease evidence before program review.
Receptor-type tyrosine-protein phosphatase epsilon
Review this target as Receptor-type tyrosine-protein phosphatase epsilon, mapped to UniProt P23469. Sequence length is 700 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Receptor-type tyrosine-protein phosphatase epsilon as ChEMBL target CHEMBL4850, mapped to UniProt P23469. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Receptor-type tyrosine-protein phosphatase epsilon |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P23469 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Receptor-type tyrosine-protein phosphatase epsilon |
| UniProt Accession | P23469 |
| Component Type | Protein |
| Sequence Length | 700 aa |
Receptor-type tyrosine-protein phosphatase epsilon
Review this target as Receptor-type tyrosine-protein phosphatase epsilon, mapped to UniProt P23469. Sequence length is 700 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4174865 | 5.73 | IC50 | 1860.0 | Preclinical |
| CHEMBL4160163 | 5.7 | IC50 | 2010.0 | Preclinical |
| CHEMBL4170383 | 5.61 | IC50 | 2470.0 | Preclinical |
| CHEMBL4168082 | 5.43 | IC50 | 3700.0 | Preclinical |
| CHEMBL4159748 | 5.38 | IC50 | 4170.0 | Preclinical |
| CHEMBL138806 | 4.7 | Ki | 20000.0 | Preclinical |
| CHEMBL336908 | 4.48 | Ki | 33000.0 | Preclinical |
| CHEMBL341806 | 4.48 | Ki | 33000.0 | Preclinical |
| CHEMBL138152 | 4.35 | Ki | 45000.0 | Preclinical |
| CHEMBL573989 | 4.35 | Ki | 45000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 18 | 10 | 4.4 |
| assay format | 3 | 5 | 5.6 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |