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Target Snapshot

CHEMBL4879426 Target Snapshot

L-lactate dehydrogenase A chain · SINGLE PROTEIN · Mus musculus

7Compounds
2Assays
0Approved Drugs
13.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P06151. Use UniProt P06151 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P06151 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats L-lactate dehydrogenase A chain as ChEMBL target CHEMBL4879426, mapped to UniProt P06151. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
L-lactate dehydrogenase A chain
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL4879426
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P06151
L-lactate dehydrogenase A chain
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether L-lactate dehydrogenase A chain is the right protein anchor across sources, using UniProt P06151 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelL-lactate dehydrogenase A chain
UniProt AccessionP06151
Component TypeProtein
Sequence Length332 aa

L-lactate dehydrogenase A chain

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as L-lactate dehydrogenase A chain, mapped to UniProt P06151. Sequence length is 332 aa.

Mapped IDP06151
Review nameL-lactate dehydrogenase A chain
OrganismMus musculus
Assay Mix

Activity Type Distribution

IC5013.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4081890 10.0 IC50 0.1 Preclinical
CHEMBL4855986 9.7 IC50 0.2 Preclinical
CHEMBL4861379 9.7 IC50 0.2 Preclinical
CHEMBL4873879 9.52 IC50 0.3 Preclinical
CHEMBL4847068 9.4 IC50 0.4 Preclinical
CHEMBL4850573 9.4 IC50 0.4 Preclinical
CHEMBL4864519 9.15 IC50 0.7 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
1
6.0
5
6.5
0
7.0
0
7.5
0
8.0
0
8.5
3
9.0
3
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
13
Tested Compounds
1
Assay Types
Binding — 2 assays, 13 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 7 9.6
tissue-based format 1 6 6.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine