Triosephosphate isomerase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P60174. Use UniProt P60174 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P60174 as the stable identity anchor, then attach disease evidence before program review.
Triosephosphate isomerase
Review this target as Triosephosphate isomerase, mapped to UniProt P60174. Sequence length is 249 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Triosephosphate isomerase as ChEMBL target CHEMBL4880, mapped to UniProt P60174. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Triosephosphate isomerase is the right protein anchor across sources, using UniProt P60174 as the stable mapping.
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| Preferred Name | Triosephosphate isomerase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P60174 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Triosephosphate isomerase |
| UniProt Accession | P60174 |
| Component Type | Protein |
| Sequence Length | 249 aa |
Triosephosphate isomerase
Review this target as Triosephosphate isomerase, mapped to UniProt P60174. Sequence length is 249 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 7.2 | Kd | 62.46 | Preclinical |
| CHEMBL3752910 | 6.74 | Kd | 182.66 | Preclinical |
| CHEMBL5222013 | 6.0 | IC50 | 990.0 | Preclinical |
| CHEMBL5592631 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL5592379 | 5.72 | IC50 | 1900.0 | Preclinical |
| CHEMBL371668 | 5.52 | Ki | 3000.0 | Preclinical |
| CHEMBL195976 | 5.35 | Ki | 4500.0 | Preclinical |
| CHEMBL5592551 | 5.1 | IC50 | 7990.0 | Preclinical |
| CHEMBL3142429 | 4.82 | Ki | 15000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 11 | 5.8 |