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Target Snapshot

CHEMBL4888483 Target Snapshot

Plasmodium · ORGANISM · Plasmodium

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50Compounds
9Assays
3Approved Drugs
50.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Plasmodium as ChEMBL target CHEMBL4888483. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Plasmodium
ORGANISM · Plasmodium
As of 2026-09-13
ChEMBL target ID
CHEMBL4888483
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Plasmodium still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NamePlasmodium
Target TypeORGANISM
OrganismPlasmodium
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPlasmodium
UniProt AccessionN/A

Plasmodium

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Plasmodium.

Review namePlasmodium
OrganismPlasmodium
Clinical Profile

Clinical Phase Distribution

3
Approved
1
Phase III
Assay Mix

Activity Type Distribution

IC5048.0
EC502.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1017 7.6 IC50 25.0 Approved
CHEMBL5620163 7.11 IC50 77.0 Preclinical
CHEMBL5619992 6.96 IC50 110.0 Preclinical
CHEMBL4780715 6.77 IC50 170.0 Preclinical
CHEMBL1200667 6.66 IC50 220.0 Clinical
CHEMBL5619557 6.6 IC50 250.0 Preclinical
CHEMBL5279304 6.54 IC50 290.0 Preclinical
CHEMBL5618607 6.41 IC50 390.0 Preclinical
CHEMBL5618127 6.39 IC50 410.0 Preclinical
CHEMBL5618483 6.32 IC50 480.0 Preclinical
Distribution

pChEMBL Value Distribution

4
5.0
7
5.5
5
6.0
5
6.5
1
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

TELMISARTAN
CHEMBL1017
Approved 1998
Properties Compare Identifier
Assay Landscape

Assay Landscape

9
Total Assays
22
Tested Compounds
1
Assay Types
Functional — 9 assays, 22 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 8 22 6.1
assay format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine