Tyrosine-protein kinase receptor UFO · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Tyrosine-protein kinase receptor UFO shows approved-linked disease relevance led by neoplasm. 5 more disease programs remain visible in the same review block. 4 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P30530. Start with neoplasm, then reuse UniProt P30530 as the stable protein anchor across project notes and exports.
Start with neoplasm, then reuse UniProt P30530 as the stable protein anchor across project notes and exports.
Tyrosine-protein kinase receptor UFO shows approved-linked disease relevance led by neoplasm. 5 more disease programs remain visible in the same review block. 4 linked drugs remain visible in the same block.
Start review with neoplasm because it currently carries approved-linked support. Linked drugs include BEMCENTINIB, BPI-9016, GILTERITINIB, MECBOTAMAB VEDOTIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyTyrosine-protein kinase receptor UFO
Review this target as Tyrosine-protein kinase receptor UFO, mapped to UniProt P30530. Sequence length is 894 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase receptor UFO as ChEMBL target CHEMBL4895, mapped to UniProt P30530. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Tyrosine-protein kinase receptor UFO is the right protein anchor across sources, using UniProt P30530 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why neoplasm is currently framed as approved-linked support. It currently carries 4 linked drugs in the same disease frame.
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| Preferred Name | Tyrosine-protein kinase receptor UFO |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P30530 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase receptor UFO |
| UniProt Accession | P30530 |
| Component Type | Protein |
| Sequence Length | 894 aa |
Tyrosine-protein kinase receptor UFO
Review this target as Tyrosine-protein kinase receptor UFO, mapped to UniProt P30530. Sequence length is 894 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Tyrosine-protein kinase receptor UFO shows approved-linked disease relevance led by neoplasm. 5 more disease programs remain visible in the same review block.
Start review with neoplasm because it currently carries approved-linked support. Linked drugs include BEMCENTINIB, BPI-9016, GILTERITINIB, MECBOTAMAB VEDOTIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5758853 | 11.0 | Ki | 0.01 | Preclinical |
| CHEMBL5935453 | 10.92 | Ki | 0.012 | Preclinical |
| CHEMBL5932919 | 10.92 | Ki | 0.012 | Preclinical |
| CHEMBL5792035 | 10.85 | Ki | 0.014 | Preclinical |
| CHEMBL5923596 | 10.82 | Ki | 0.015 | Preclinical |
| CHEMBL5930737 | 10.82 | Ki | 0.015 | Preclinical |
| CHEMBL5906788 | 10.8 | Ki | 0.016 | Preclinical |
| CHEMBL5931969 | 10.8 | Ki | 0.016 | Preclinical |
| CHEMBL6041852 | 10.8 | Ki | 0.016 | Preclinical |
| CHEMBL5819606 | 10.74 | Ki | 0.018 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 485 | 1,914 | 6.7 |
| cell-based format | 84 | 256 | 7.6 |
| assay format | 58 | 495 | 8.5 |
| subcellular format | 16 | 2 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 168 | 7.0 |
| cell-based format | 1 | 1 | 6.8 |