Low molecular weight phosphotyrosine protein phosphatase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P24666. Use UniProt P24666 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P24666 as the stable identity anchor, then attach disease evidence before program review.
Low molecular weight phosphotyrosine protein phosphatase
Review this target as Low molecular weight phosphotyrosine protein phosphatase, mapped to UniProt P24666. Sequence length is 158 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Low molecular weight phosphotyrosine protein phosphatase as ChEMBL target CHEMBL4903, mapped to UniProt P24666. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Low molecular weight phosphotyrosine protein phosphatase is the right protein anchor across sources, using UniProt P24666 as the stable mapping.
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| Preferred Name | Low molecular weight phosphotyrosine protein phosphatase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P24666 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Low molecular weight phosphotyrosine protein phosphatase |
| UniProt Accession | P24666 |
| Component Type | Protein |
| Sequence Length | 158 aa |
Low molecular weight phosphotyrosine protein phosphatase
Review this target as Low molecular weight phosphotyrosine protein phosphatase, mapped to UniProt P24666. Sequence length is 158 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5218807 | 8.92 | Ki | 1.2 | Preclinical |
| CHEMBL5218807 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4875137 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL5219822 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL4856707 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL5653589 | 7.4 | Kd | 39.49 | Preclinical |
| CHEMBL5218783 | 7.31 | IC50 | 49.0 | Preclinical |
| CHEMBL5220687 | 7.25 | IC50 | 56.0 | Preclinical |
| CHEMBL4857535 | 7.08 | IC50 | 83.0 | Preclinical |
| CHEMBL4855952 | 7.06 | IC50 | 87.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 39 | 332 | 5.7 |
| assay format | 26 | 79 | 5.2 |
| cell-based format | 14 | 33 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 34 | 5.0 |