Galectin-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Galectin-1 shows clinical signal disease relevance led by bile duct carcinoma. 3 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt P09382. Start with bile duct carcinoma, then reuse UniProt P09382 as the stable protein anchor across project notes and exports.
Start with bile duct carcinoma, then reuse UniProt P09382 as the stable protein anchor across project notes and exports.
Galectin-1 shows clinical signal disease relevance led by bile duct carcinoma. 3 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with bile duct carcinoma because it currently carries clinical signal support. Linked drugs include DAVANAT. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyGalectin-1
Review this target as Galectin-1, mapped to UniProt P09382. Sequence length is 135 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Galectin-1 as ChEMBL target CHEMBL4915, mapped to UniProt P09382. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Galectin-1 is the right protein anchor across sources, using UniProt P09382 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why bile duct carcinoma is currently framed as clinical signal support. It currently carries 1 linked drug in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Galectin-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P09382 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Galectin-1 |
| UniProt Accession | P09382 |
| Component Type | Protein |
| Sequence Length | 135 aa |
Galectin-1
Review this target as Galectin-1, mapped to UniProt P09382. Sequence length is 135 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Galectin-1 shows clinical signal disease relevance led by bile duct carcinoma. 3 more disease programs remain visible in the same review block.
Start review with bile duct carcinoma because it currently carries clinical signal support. Linked drugs include DAVANAT. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5512479 | 8.4 | Kd | 4.0 | Preclinical |
| CHEMBL5866001 | 8.22 | Kd | 6.0 | Preclinical |
| CHEMBL4091143 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL4297442 | 7.92 | Kd | 12.0 | Clinical |
| CHEMBL2313626 | 7.89 | Kd | 13.0 | Preclinical |
| CHEMBL5925466 | 7.89 | Kd | 13.0 | Preclinical |
| CHEMBL5829222 | 7.72 | Kd | 19.0 | Preclinical |
| CHEMBL5505811 | 7.7 | Kd | 20.0 | Preclinical |
| CHEMBL4065371 | 7.57 | Kd | 27.0 | Preclinical |
| CHEMBL5921738 | 7.57 | Kd | 27.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 79 | 213 | 6.2 |
| assay format | 12 | 86 | 5.5 |
| cell-based format | 4 | 0 | — |
| tissue-based format | 1 | 0 | — |