Urotensin-2 receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P49684. Use UniProt P49684 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P49684 as the stable identity anchor, then attach disease evidence before program review.
Urotensin-2 receptor
Review this target as Urotensin-2 receptor, mapped to UniProt P49684. Sequence length is 386 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Urotensin-2 receptor as ChEMBL target CHEMBL4921, mapped to UniProt P49684. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Urotensin-2 receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P49684 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Urotensin-2 receptor |
| UniProt Accession | P49684 |
| Component Type | Protein |
| Sequence Length | 386 aa |
Urotensin-2 receptor
Review this target as Urotensin-2 receptor, mapped to UniProt P49684. Sequence length is 386 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3315148 | 10.9 | EC50 | 0.01259 | Preclinical |
| CHEMBL3315144 | 10.71 | EC50 | 0.0195 | Preclinical |
| CHEMBL1165797 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL218994 | 10.0 | EC50 | 0.1 | Preclinical |
| CHEMBL1165734 | 9.96 | EC50 | 0.11 | Preclinical |
| CHEMBL577772 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL1163460 | 9.8 | EC50 | 0.16 | Preclinical |
| CHEMBL1163463 | 9.77 | EC50 | 0.17 | Preclinical |
| CHEMBL1163463 | 9.72 | Ki | 0.19 | Preclinical |
| CHEMBL390094 | 9.6 | EC50 | 0.2512 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 59 | 71 | 7.9 |
| tissue-based format | 8 | 21 | 8.6 |
| cell-based format | 2 | 10 | 8.3 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 20 | 13 | 7.9 |
| cell-based format | 10 | 86 | 7.5 |
| tissue-based format | 5 | 12 | 8.2 |