L-lactate dehydrogenase B chain · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P07195. Use UniProt P07195 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07195 as the stable identity anchor, then attach disease evidence before program review.
L-lactate dehydrogenase B chain
Review this target as L-lactate dehydrogenase B chain, mapped to UniProt P07195. Sequence length is 334 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats L-lactate dehydrogenase B chain as ChEMBL target CHEMBL4940, mapped to UniProt P07195. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether L-lactate dehydrogenase B chain is the right protein anchor across sources, using UniProt P07195 as the stable mapping.
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| Preferred Name | L-lactate dehydrogenase B chain |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07195 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | L-lactate dehydrogenase B chain |
| UniProt Accession | P07195 |
| Component Type | Protein |
| Sequence Length | 334 aa |
L-lactate dehydrogenase B chain
Review this target as L-lactate dehydrogenase B chain, mapped to UniProt P07195. Sequence length is 334 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5185237 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL5201115 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL5181496 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL4065858 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL4753379 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL4059985 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL5196929 | 8.09 | IC50 | 8.2 | Preclinical |
| CHEMBL3752910 | 8.08 | Kd | 8.312 | Preclinical |
| CHEMBL5172378 | 8.05 | IC50 | 8.9 | Preclinical |
| CHEMBL5194549 | 8.02 | IC50 | 9.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 33 | 54 | 5.7 |
| single protein format | 32 | 175 | 5.8 |
| cell-based format | 2 | 13 | 4.9 |
| tissue-based format | 1 | 1 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |