Acetylcholine receptor subunit epsilon · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P09660. Use UniProt P09660 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P09660 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholine receptor subunit epsilon
Review this target as Acetylcholine receptor subunit epsilon, mapped to UniProt P09660. Sequence length is 494 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetylcholine receptor subunit epsilon as ChEMBL target CHEMBL4961, mapped to UniProt P09660. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetylcholine receptor subunit epsilon |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P09660 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholine receptor subunit epsilon |
| UniProt Accession | P09660 |
| Component Type | Protein |
| Sequence Length | 494 aa |
Acetylcholine receptor subunit epsilon
Review this target as Acetylcholine receptor subunit epsilon, mapped to UniProt P09660. Sequence length is 494 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4571835 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL3120178 | 5.1 | IC50 | 7943.28 | Preclinical |
| CHEMBL4594074 | 5.08 | IC50 | 8300.0 | Preclinical |
| CHEMBL4459614 | 5.06 | IC50 | 8800.0 | Preclinical |
| CHEMBL636 | 5.05 | IC50 | 9000.0 | Approved |
| CHEMBL3121479 | 5.0 | IC50 | 10000.0 | Preclinical |
| CHEMBL3121478 | 4.99 | IC50 | 10232.93 | Preclinical |
| CHEMBL4470950 | 4.87 | IC50 | 13600.0 | Preclinical |
| CHEMBL4468053 | 4.79 | IC50 | 16300.0 | Preclinical |
| CHEMBL4452617 | 4.74 | IC50 | 18100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 3 | 7 | 4.8 |
| assay format | 2 | 15 | 4.7 |