Beta-ketoacyl-ACP-synthase III · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-14Protein identity stays anchored to UniProt O77078. Use UniProt O77078 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O77078 as the stable identity anchor, then attach disease evidence before program review.
Beta-ketoacyl-acyl carrier protein synthase III
Review this target as Beta-ketoacyl-ACP-synthase III, mapped to UniProt O77078. ChEMBL maps the protein component as Beta-ketoacyl-acyl carrier protein synthase III. Sequence length is 371 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-ketoacyl-ACP-synthase III as ChEMBL target CHEMBL4968, mapped to UniProt O77078. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-ketoacyl-ACP-synthase III |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | O77078 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-ketoacyl-acyl carrier protein synthase III |
| UniProt Accession | O77078 |
| Component Type | Protein |
| Sequence Length | 371 aa |
Beta-ketoacyl-acyl carrier protein synthase III
Review this target as Beta-ketoacyl-ACP-synthase III, mapped to UniProt O77078. ChEMBL maps the protein component as Beta-ketoacyl-acyl carrier protein synthase III. Sequence length is 371 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL491752 | 7.56 | IC50 | 27.45 | Preclinical |
| CHEMBL512926 | 7.53 | IC50 | 29.6 | Preclinical |
| CHEMBL455414 | 7.33 | IC50 | 46.5 | Preclinical |
| CHEMBL445555 | 7.14 | IC50 | 72.6 | Preclinical |
| CHEMBL509952 | 7.13 | IC50 | 73.6 | Preclinical |
| CHEMBL460104 | 6.89 | IC50 | 128.7 | Preclinical |
| CHEMBL462205 | 6.55 | IC50 | 278.7 | Preclinical |
| CHEMBL451059 | 6.47 | IC50 | 341.1 | Preclinical |
| CHEMBL462374 | 6.41 | IC50 | 393.0 | Preclinical |
| CHEMBL454282 | 5.85 | IC50 | 1425.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 10 | 6.9 |
| cell-based format | 2 | 0 | — |