Cytochrome P450 2C11 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P08683. Use UniProt P08683 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08683 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 2C11
Review this target as Cytochrome P450 2C11, mapped to UniProt P08683. Sequence length is 500 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 2C11 as ChEMBL target CHEMBL4971, mapped to UniProt P08683. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 2C11 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P08683 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 2C11 |
| UniProt Accession | P08683 |
| Component Type | Protein |
| Sequence Length | 500 aa |
Cytochrome P450 2C11
Review this target as Cytochrome P450 2C11, mapped to UniProt P08683. Sequence length is 500 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL301982 | 5.15 | Ki | 7050.0 | Preclinical |
| CHEMBL301982 | 4.99 | IC50 | 10200.0 | Preclinical |
| CHEMBL328863 | 4.69 | IC50 | 20400.0 | Preclinical |
| CHEMBL190461 | 4.68 | Ki | 20700.0 | Approved |
| CHEMBL319160 | 4.46 | IC50 | 34300.0 | Preclinical |
| CHEMBL157101 | 4.08 | IC50 | 84100.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 4 | 4.7 |
| microsome format | 3 | 1 | 4.7 |
| assay format | 2 | 0 | — |