5-hydroxytryptamine receptor 3A · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P23979. Use UniProt P23979 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23979 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 3A
Review this target as 5-hydroxytryptamine receptor 3A, mapped to UniProt P23979. Sequence length is 489 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 3A as ChEMBL target CHEMBL4972, mapped to UniProt P23979. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 5-hydroxytryptamine receptor 3A is the right protein anchor across sources, using UniProt P23979 as the stable mapping.
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| Preferred Name | 5-hydroxytryptamine receptor 3A |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P23979 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 3A |
| UniProt Accession | P23979 |
| Component Type | Protein |
| Sequence Length | 489 aa |
5-hydroxytryptamine receptor 3A
Review this target as 5-hydroxytryptamine receptor 3A, mapped to UniProt P23979. Sequence length is 489 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL608735 | 8.92 | Ki | 1.2 | Preclinical |
| CHEMBL597842 | 8.47 | Ki | 3.4 | Preclinical |
| CHEMBL598873 | 8.41 | Ki | 3.9 | Preclinical |
| CHEMBL611082 | 7.89 | Ki | 13.0 | Preclinical |
| CHEMBL42 | 7.5 | Ki | 32.0 | Approved |
| CHEMBL2436555 | 7.1 | Ki | 80.0 | Preclinical |
| CHEMBL605715 | 7.04 | Ki | 92.0 | Preclinical |
| CHEMBL597681 | 6.9 | Ki | 126.0 | Preclinical |
| CHEMBL601899 | 6.85 | Ki | 141.0 | Preclinical |
| CHEMBL598045 | 6.79 | Ki | 162.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 20 | 6 | 5.3 |
| cell-based format | 6 | 30 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 21 | 2 | 5.1 |