Transcription factor Jun · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P05412. Use UniProt P05412 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05412 as the stable identity anchor, then attach disease evidence before program review.
Transcription factor Jun
Review this target as Transcription factor Jun, mapped to UniProt P05412. Sequence length is 331 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transcription factor Jun as ChEMBL target CHEMBL4977, mapped to UniProt P05412. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Transcription factor Jun is the right protein anchor across sources, using UniProt P05412 as the stable mapping.
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| Preferred Name | Transcription factor Jun |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P05412 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcription factor Jun |
| UniProt Accession | P05412 |
| Component Type | Protein |
| Sequence Length | 331 aa |
Transcription factor Jun
Review this target as Transcription factor Jun, mapped to UniProt P05412. Sequence length is 331 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL337665 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL129857 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL132495 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL1761563 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL43549 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL487194 | 7.5 | IC50 | 32.0 | Preclinical |
| CHEMBL85822 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL1761561 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL1761582 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL1761583 | 7.4 | IC50 | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 64 | 93 | 5.9 |
| single protein format | 13 | 33 | 6.1 |
| assay format | 1 | 9 | 5.2 |