Prostaglandin F2-alpha receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P43117. Use UniProt P43117 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P43117 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin F2-alpha receptor
Review this target as Prostaglandin F2-alpha receptor, mapped to UniProt P43117. Sequence length is 366 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin F2-alpha receptor as ChEMBL target CHEMBL5000, mapped to UniProt P43117. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin F2-alpha receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P43117 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin F2-alpha receptor |
| UniProt Accession | P43117 |
| Component Type | Protein |
| Sequence Length | 366 aa |
Prostaglandin F2-alpha receptor
Review this target as Prostaglandin F2-alpha receptor, mapped to UniProt P43117. Sequence length is 366 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL491667 | 8.72 | EC50 | 1.9 | Preclinical |
| CHEMBL4643852 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL521964 | 8.24 | EC50 | 5.7 | Preclinical |
| CHEMBL1050 | 8.2 | EC50 | 6.31 | Preclinical |
| CHEMBL815 | 7.9 | EC50 | 12.59 | Approved |
| CHEMBL1910324 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL491474 | 7.28 | EC50 | 52.4 | Preclinical |
| CHEMBL489109 | 7.21 | EC50 | 62.2 | Preclinical |
| CHEMBL491475 | 7.16 | EC50 | 68.6 | Preclinical |
| CHEMBL523143 | 6.53 | EC50 | 294.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 18 | 0 | — |
| cell-based format | 5 | 9 | 6.1 |
| single protein format | 3 | 1 | 8.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 10 | 7.3 |
| assay format | 3 | 1 | 7.9 |