Sphingosine-1-phosphate lyase 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q8R0X7. Use UniProt Q8R0X7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8R0X7 as the stable identity anchor, then attach disease evidence before program review.
Sphingosine-1-phosphate lyase 1
Review this target as Sphingosine-1-phosphate lyase 1, mapped to UniProt Q8R0X7. Sequence length is 568 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sphingosine-1-phosphate lyase 1 as ChEMBL target CHEMBL5009, mapped to UniProt Q8R0X7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sphingosine-1-phosphate lyase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q8R0X7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sphingosine-1-phosphate lyase 1 |
| UniProt Accession | Q8R0X7 |
| Component Type | Protein |
| Sequence Length | 568 aa |
Sphingosine-1-phosphate lyase 1
Review this target as Sphingosine-1-phosphate lyase 1, mapped to UniProt Q8R0X7. Sequence length is 568 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL491458 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL314854 | 4.28 | IC50 | 52400.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 2 | 1 | 5.7 |
| microsome format | 1 | 1 | 4.3 |