Monoacylglycerol lipase ABHD6 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8R2Y0. Use UniProt Q8R2Y0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8R2Y0 as the stable identity anchor, then attach disease evidence before program review.
Monoacylglycerol lipase ABHD6
Review this target as Monoacylglycerol lipase ABHD6, mapped to UniProt Q8R2Y0. Sequence length is 336 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Monoacylglycerol lipase ABHD6 as ChEMBL target CHEMBL5010, mapped to UniProt Q8R2Y0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Monoacylglycerol lipase ABHD6 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q8R2Y0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Monoacylglycerol lipase ABHD6 |
| UniProt Accession | Q8R2Y0 |
| Component Type | Protein |
| Sequence Length | 336 aa |
Monoacylglycerol lipase ABHD6
Review this target as Monoacylglycerol lipase ABHD6, mapped to UniProt Q8R2Y0. Sequence length is 336 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3263577 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3263579 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3263582 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3318603 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL3318604 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL3318612 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5274434 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL3913807 | 7.3 | IC50 | 50.12 | Preclinical |
| CHEMBL606201 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL3318590 | 7.22 | IC50 | 60.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 26 | 56 | 6.4 |
| tissue-based format | 15 | 4 | 8.0 |
| cell-based format | 11 | 6 | 8.3 |
| assay format | 2 | 32 | 6.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |