Tyrosine-protein kinase TEC · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8CFK4. Use UniProt Q8CFK4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8CFK4 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase
Review this target as Tyrosine-protein kinase TEC, mapped to UniProt Q8CFK4. ChEMBL maps the protein component as Tyrosine-protein kinase. Sequence length is 608 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase TEC as ChEMBL target CHEMBL5025, mapped to UniProt Q8CFK4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein kinase TEC |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q8CFK4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase |
| UniProt Accession | Q8CFK4 |
| Component Type | Protein |
| Sequence Length | 608 aa |
Tyrosine-protein kinase
Review this target as Tyrosine-protein kinase TEC, mapped to UniProt Q8CFK4. ChEMBL maps the protein component as Tyrosine-protein kinase. Sequence length is 608 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL185932 | 4.66 | Kd | 22000.0 | Preclinical |
| CHEMBL426622 | 4.58 | EC50 | 26000.0 | Preclinical |
| CHEMBL366327 | 4.47 | EC50 | 34000.0 | Preclinical |
| CHEMBL366327 | 4.4 | Kd | 40000.0 | Preclinical |
| CHEMBL426622 | 4.28 | Kd | 52000.0 | Preclinical |
| CHEMBL189197 | 4.24 | EC50 | 58000.0 | Preclinical |
| CHEMBL361660 | 4.21 | Kd | 61000.0 | Preclinical |
| CHEMBL188730 | 4.2 | EC50 | 63000.0 | Preclinical |
| CHEMBL189514 | 4.12 | EC50 | 76000.0 | Preclinical |
| CHEMBL361660 | 4.12 | EC50 | 75000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 13 | 4.3 |