Disintegrin and metalloproteinase domain-containing protein 10 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O14672. Use UniProt O14672 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O14672 as the stable identity anchor, then attach disease evidence before program review.
Disintegrin and metalloproteinase domain-containing protein 10
Review this target as Disintegrin and metalloproteinase domain-containing protein 10, mapped to UniProt O14672. Sequence length is 748 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Disintegrin and metalloproteinase domain-containing protein 10 as ChEMBL target CHEMBL5028, mapped to UniProt O14672. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Disintegrin and metalloproteinase domain-containing protein 10 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O14672 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Disintegrin and metalloproteinase domain-containing protein 10 |
| UniProt Accession | O14672 |
| Component Type | Protein |
| Sequence Length | 748 aa |
Disintegrin and metalloproteinase domain-containing protein 10
Review this target as Disintegrin and metalloproteinase domain-containing protein 10, mapped to UniProt O14672. Sequence length is 748 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4435465 | 8.28 | IC50 | 5.3 | Preclinical |
| CHEMBL5206579 | 8.28 | IC50 | 5.3 | Preclinical |
| CHEMBL442432 | 8.21 | IC50 | 6.2 | Preclinical |
| CHEMBL253021 | 8.19 | IC50 | 6.5 | Preclinical |
| CHEMBL251820 | 8.15 | IC50 | 7.1 | Preclinical |
| CHEMBL400528 | 8.11 | IC50 | 7.8 | Preclinical |
| CHEMBL19611 | 8.09 | IC50 | 8.1 | Clinical |
| CHEMBL569388 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL3770688 | 8.04 | IC50 | 9.2 | Preclinical |
| CHEMBL584116 | 8.02 | IC50 | 9.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 44 | 150 | 7.0 |
| cell-based format | 16 | 65 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 1 | 4.9 |
| single protein format | 2 | 2 | 6.0 |