Use UniProt Q8MMZ8 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5036 Target Snapshot
cGMP-dependent protein kinase · SINGLE PROTEIN · Eimeria tenella
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As of 2026-09-15Protein identity stays anchored to UniProt Q8MMZ8. Use UniProt Q8MMZ8 as the stable identity anchor, then attach disease evidence before program review.
cGMP-dependent protein kinase
Review this target as cGMP-dependent protein kinase, mapped to UniProt Q8MMZ8. Sequence length is 1003 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats cGMP-dependent protein kinase as ChEMBL target CHEMBL5036, mapped to UniProt Q8MMZ8. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | cGMP-dependent protein kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Eimeria tenella |
| UniProt | Q8MMZ8 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | cGMP-dependent protein kinase |
| UniProt Accession | Q8MMZ8 |
| Component Type | Protein |
| Sequence Length | 1003 aa |
cGMP-dependent protein kinase
How to read this target
Review this target as cGMP-dependent protein kinase, mapped to UniProt Q8MMZ8. Sequence length is 1003 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL250994 | 10.59 | IC50 | 0.026 | Preclinical |
| CHEMBL207971 | 10.4 | IC50 | 0.04 | Preclinical |
| CHEMBL497187 | 10.36 | IC50 | 0.044 | Preclinical |
| CHEMBL207476 | 10.34 | IC50 | 0.046 | Preclinical |
| CHEMBL370263 | 10.34 | IC50 | 0.046 | Preclinical |
| CHEMBL428900 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL248768 | 10.25 | IC50 | 0.056 | Preclinical |
| CHEMBL233009 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL250391 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL400908 | 10.22 | IC50 | 0.06 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 12 assays, 256 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 256 | 9.2 |