Use UniProt P32523 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5058 Target Snapshot
Pre-mRNA-processing factor 19 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-14Protein identity stays anchored to UniProt P32523. Use UniProt P32523 as the stable identity anchor, then attach disease evidence before program review.
Pre-mRNA-processing factor 19
Review this target as Pre-mRNA-processing factor 19, mapped to UniProt P32523. Sequence length is 503 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Pre-mRNA-processing factor 19 as ChEMBL target CHEMBL5058, mapped to UniProt P32523. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Pre-mRNA-processing factor 19 is the right protein anchor across sources, using UniProt P32523 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Pre-mRNA-processing factor 19 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P32523 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pre-mRNA-processing factor 19 |
| UniProt Accession | P32523 |
| Component Type | Protein |
| Sequence Length | 503 aa |
Pre-mRNA-processing factor 19
How to read this target
Review this target as Pre-mRNA-processing factor 19, mapped to UniProt P32523. Sequence length is 503 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL447931 | 6.92 | EC50 | 121.0 | Preclinical |
| CHEMBL21241 | 6.75 | EC50 | 178.0 | Preclinical |
| CHEMBL456820 | 6.74 | EC50 | 183.0 | Preclinical |
| CHEMBL514739 | 6.65 | EC50 | 223.0 | Preclinical |
| CHEMBL501616 | 6.33 | EC50 | 467.0 | Preclinical |
| CHEMBL457440 | 6.28 | EC50 | 524.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 1 assays, 6 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 6 | 6.6 |