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Target Snapshot

CHEMBL5058522 Target Snapshot

Tubulin beta chain · SINGLE PROTEIN · Encephalitozoon intestinalis

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Tubulin beta chain shows clinical signal disease relevance led by Helminthiasis. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt Q9GSR5. Start with Helminthiasis, then reuse UniProt Q9GSR5 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with Helminthiasis, then reuse UniProt Q9GSR5 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14 1 linked drug
Open source guide
Disease program
Helminthiasis

Tubulin beta chain shows clinical signal disease relevance led by Helminthiasis. 1 linked drug remains visible in the same block.

Start review with Helminthiasis because it currently carries clinical signal support. Linked drugs include FENBENDAZOLE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Clinical signal Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Tubulin beta chain as ChEMBL target CHEMBL5058522, mapped to UniProt Q9GSR5. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Tubulin beta chain
SINGLE PROTEIN · Encephalitozoon intestinalis
As of 2026-09-14
ChEMBL target ID
CHEMBL5058522
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9GSR5
Tubulin beta chain
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Tubulin beta chain is the right protein anchor across sources, using UniProt Q9GSR5 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why Helminthiasis is currently framed as clinical signal support. It currently carries 1 linked drug in the same disease frame.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTubulin beta chain
UniProt AccessionQ9GSR5
Component TypeProtein
Sequence Length439 aa

Tubulin beta chain

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Tubulin beta chain, mapped to UniProt Q9GSR5. Sequence length is 439 aa.

Mapped IDQ9GSR5
Review nameTubulin beta chain
OrganismEncephalitozoon intestinalis
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Clinical signal Open Targets-ready proxy

Tubulin beta chain shows clinical signal disease relevance led by Helminthiasis.

Clinical signal Phase II
Helminthiasis
1 linked drug · 1 direct · 1 efficacy
Linked drugFENBENDAZOLE
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with Helminthiasis because it currently carries clinical signal support. Linked drugs include FENBENDAZOLE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseaseHelminthiasis
Strongest levelClinical signal
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine