Use UniProt O19045 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5062 Target Snapshot
Coagulation factor X · SINGLE PROTEIN · Oryctolagus cuniculus
Research home keeps recent targets
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Switch target
Move to another high-traffic target or paste a specific ChEMBL target ID.
Frame the target before identity details
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt O19045. Use UniProt O19045 as the stable identity anchor, then attach disease evidence before program review.
Coagulation factor X
Review this target as Coagulation factor X, mapped to UniProt O19045. Sequence length is 490 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Coagulation factor X as ChEMBL target CHEMBL5062, mapped to UniProt O19045. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Coagulation factor X is the right protein anchor across sources, using UniProt O19045 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Coagulation factor X |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | O19045 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Coagulation factor X |
| UniProt Accession | O19045 |
| Component Type | Protein |
| Sequence Length | 490 aa |
Coagulation factor X
How to read this target
Review this target as Coagulation factor X, mapped to UniProt O19045. Sequence length is 490 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL152854 | 10.52 | Ki | 0.03 | Preclinical |
| CHEMBL378093 | 10.22 | Ki | 0.06 | Preclinical |
| CHEMBL156924 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL474678 | 9.97 | IC50 | 0.108 | Preclinical |
| CHEMBL7651 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL558198 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL231779 | 9.77 | Ki | 0.17 | Approved |
| CHEMBL436766 | 9.77 | Ki | 0.17 | Preclinical |
| CHEMBL206335 | 9.72 | Ki | 0.19 | Clinical |
| CHEMBL438647 | 9.7 | Ki | 0.2 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 35 assays, 127 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 35 | 127 | 7.4 |