Prostaglandin E2 receptor EP1 subtype · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P70597. Use UniProt P70597 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P70597 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin E2 receptor EP1 subtype
Review this target as Prostaglandin E2 receptor EP1 subtype, mapped to UniProt P70597. Sequence length is 405 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin E2 receptor EP1 subtype as ChEMBL target CHEMBL5068, mapped to UniProt P70597. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin E2 receptor EP1 subtype |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P70597 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin E2 receptor EP1 subtype |
| UniProt Accession | P70597 |
| Component Type | Protein |
| Sequence Length | 405 aa |
Prostaglandin E2 receptor EP1 subtype
Review this target as Prostaglandin E2 receptor EP1 subtype, mapped to UniProt P70597. Sequence length is 405 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4085914 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL4105205 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL4081524 | 8.21 | IC50 | 6.2 | Preclinical |
| CHEMBL4074797 | 8.19 | IC50 | 6.4 | Preclinical |
| CHEMBL4100262 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL4064816 | 8.03 | IC50 | 9.4 | Preclinical |
| CHEMBL4104333 | 8.0 | IC50 | 9.9 | Preclinical |
| CHEMBL3665552 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL4083796 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL362851 | 7.92 | Ki | 12.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 144 | 6.8 |
| tissue-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 7.9 |
| cell-based format | 1 | 0 | — |
| single protein format | 1 | 1 | 7.9 |