Hypoxanthine-guanine phosphoribosyltransferase · SINGLE PROTEIN · Trypanosoma brucei brucei
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q07010. Use UniProt Q07010 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q07010 as the stable identity anchor, then attach disease evidence before program review.
Hypoxanthine-guanine phosphoribosyltransferase
Review this target as Hypoxanthine-guanine phosphoribosyltransferase, mapped to UniProt Q07010. Sequence length is 210 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Hypoxanthine-guanine phosphoribosyltransferase as ChEMBL target CHEMBL5069, mapped to UniProt Q07010. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Hypoxanthine-guanine phosphoribosyltransferase is the right protein anchor across sources, using UniProt Q07010 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Hypoxanthine-guanine phosphoribosyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei brucei |
| UniProt | Q07010 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Hypoxanthine-guanine phosphoribosyltransferase |
| UniProt Accession | Q07010 |
| Component Type | Protein |
| Sequence Length | 210 aa |
Hypoxanthine-guanine phosphoribosyltransferase
Review this target as Hypoxanthine-guanine phosphoribosyltransferase, mapped to UniProt Q07010. Sequence length is 210 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1161675 | 4.63 | Ki | 23200.0 | Preclinical |
| CHEMBL834 | 4.3 | Ki | 50600.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 4 | 4.5 |