Endothelial lipase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9Y5X9. Use UniProt Q9Y5X9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Y5X9 as the stable identity anchor, then attach disease evidence before program review.
Endothelial lipase
Review this target as Endothelial lipase, mapped to UniProt Q9Y5X9. Sequence length is 500 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Endothelial lipase as ChEMBL target CHEMBL5080, mapped to UniProt Q9Y5X9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Endothelial lipase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9Y5X9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Endothelial lipase |
| UniProt Accession | Q9Y5X9 |
| Component Type | Protein |
| Sequence Length | 500 aa |
Endothelial lipase
Review this target as Endothelial lipase, mapped to UniProt Q9Y5X9. Sequence length is 500 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3672653 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3672654 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677433 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677434 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677439 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677528 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677556 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677557 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3677634 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL3682491 | 9.3 | IC50 | 0.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 30 | 242 | 6.7 |
| single protein format | 19 | 401 | 7.5 |
| assay format | 1 | 587 | 7.8 |
| cell-free format | 1 | 14 | 7.0 |