Muscarinic acetylcholine receptor M3 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q9ERZ3. Use UniProt Q9ERZ3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9ERZ3 as the stable identity anchor, then attach disease evidence before program review.
Muscarinic acetylcholine receptor M3
Review this target as Muscarinic acetylcholine receptor M3, mapped to UniProt Q9ERZ3. Sequence length is 589 aa.
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This review treats Muscarinic acetylcholine receptor M3 as ChEMBL target CHEMBL5105, mapped to UniProt Q9ERZ3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Muscarinic acetylcholine receptor M3 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9ERZ3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Muscarinic acetylcholine receptor M3 |
| UniProt Accession | Q9ERZ3 |
| Component Type | Protein |
| Sequence Length | 589 aa |
Muscarinic acetylcholine receptor M3
Review this target as Muscarinic acetylcholine receptor M3, mapped to UniProt Q9ERZ3. Sequence length is 589 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL277014 | 5.96 | EC50 | 1100.0 | Preclinical |
| CHEMBL12378 | 5.55 | EC50 | 2800.0 | Preclinical |
| CHEMBL281411 | 5.24 | EC50 | 5800.0 | Preclinical |
| CHEMBL14 | 5.0 | EC50 | 9900.0 | Approved |
| CHEMBL20835 | 5.0 | EC50 | 10000.0 | Clinical |
| CHEMBL416736 | 5.0 | EC50 | 10000.0 | Preclinical |
| CHEMBL21536 | 4.96 | EC50 | 11000.0 | Approved |
| CHEMBL22089 | 4.96 | EC50 | 11000.0 | Preclinical |
| CHEMBL7303 | 4.92 | EC50 | 12000.0 | Preclinical |
| CHEMBL557795 | 4.92 | EC50 | 12000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |
| cell-based format | 2 | 14 | 5.0 |