Phosphodiesterase 3B · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt E1BN64. Use UniProt E1BN64 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt E1BN64 as the stable identity anchor, then attach disease evidence before program review.
Phosphodiesterase
Review this target as Phosphodiesterase 3B, mapped to UniProt E1BN64. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 1115 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphodiesterase 3B as ChEMBL target CHEMBL5129, mapped to UniProt E1BN64. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphodiesterase 3B |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | E1BN64 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphodiesterase |
| UniProt Accession | E1BN64 |
| Component Type | Protein |
| Sequence Length | 1115 aa |
Phosphodiesterase
Review this target as Phosphodiesterase 3B, mapped to UniProt E1BN64. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 1115 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL103976 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL319217 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL395336 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL304389 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL189 | 6.0 | IC50 | 1000.0 | Approved |
| CHEMBL102807 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL308249 | 5.46 | IC50 | 3500.0 | Preclinical |
| CHEMBL306666 | 5.22 | IC50 | 6000.0 | Preclinical |
| CHEMBL431377 | 5.16 | IC50 | 7000.0 | Preclinical |
| CHEMBL138658 | 5.04 | IC50 | 9200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 16 | 57 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |