Potassium voltage-gated channel subfamily KQT member 1 · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt O70344. Use UniProt O70344 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O70344 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily KQT member 1
Review this target as Potassium voltage-gated channel subfamily KQT member 1, mapped to UniProt O70344. Sequence length is 671 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium voltage-gated channel subfamily KQT member 1 as ChEMBL target CHEMBL5135, mapped to UniProt O70344. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Potassium voltage-gated channel subfamily KQT member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | O70344 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily KQT member 1 |
| UniProt Accession | O70344 |
| Component Type | Protein |
| Sequence Length | 671 aa |
Potassium voltage-gated channel subfamily KQT member 1
Review this target as Potassium voltage-gated channel subfamily KQT member 1, mapped to UniProt O70344. Sequence length is 671 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL488372 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL125327 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL475724 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL484801 | 8.24 | IC50 | 5.8 | Preclinical |
| CHEMBL338973 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL520069 | 8.02 | IC50 | 9.5 | Preclinical |
| CHEMBL124448 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL125000 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL475111 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL124545 | 7.64 | IC50 | 23.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 22 | 6.3 |
| assay format | 1 | 20 | 6.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 2 | 6.1 |