Platelet-activating factor receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt P21556. Use UniProt P21556 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21556 as the stable identity anchor, then attach disease evidence before program review.
Platelet-activating factor receptor
Review this target as Platelet-activating factor receptor, mapped to UniProt P21556. Sequence length is 342 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Platelet-activating factor receptor as ChEMBL target CHEMBL5136, mapped to UniProt P21556. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Platelet-activating factor receptor is the right protein anchor across sources, using UniProt P21556 as the stable mapping.
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| Preferred Name | Platelet-activating factor receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P21556 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Platelet-activating factor receptor |
| UniProt Accession | P21556 |
| Component Type | Protein |
| Sequence Length | 342 aa |
Platelet-activating factor receptor
Review this target as Platelet-activating factor receptor, mapped to UniProt P21556. Sequence length is 342 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL174592 | 9.82 | Ki | 0.15 | Preclinical |
| CHEMBL368113 | 9.72 | Ki | 0.19 | Preclinical |
| CHEMBL119660 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL95440 | 9.43 | Ki | 0.37 | Preclinical |
| CHEMBL322832 | 9.4 | Ki | 0.4 | Clinical |
| CHEMBL420527 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL334275 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL119371 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL324709 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL106908 | 9.3 | IC50 | 0.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 29 | 221 | 7.0 |
| cell membrane format | 4 | 71 | 7.5 |
| single protein format | 3 | 12 | 6.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 25 | 601 | 6.7 |
| cell membrane format | 1 | 93 | 7.9 |
| cell-free format | 1 | 25 | 5.6 |
| organism-based format | 1 | 0 | — |