Luciferin 4-monooxygenase · SINGLE PROTEIN · Photuris pennsylvanica
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q27757. Use UniProt Q27757 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q27757 as the stable identity anchor, then attach disease evidence before program review.
Luciferin 4-monooxygenase
Review this target as Luciferin 4-monooxygenase, mapped to UniProt Q27757. Sequence length is 545 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Luciferin 4-monooxygenase as ChEMBL target CHEMBL5150, mapped to UniProt Q27757. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Luciferin 4-monooxygenase |
| Target Type | SINGLE PROTEIN |
| Organism | Photuris pennsylvanica |
| UniProt | Q27757 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Luciferin 4-monooxygenase |
| UniProt Accession | Q27757 |
| Component Type | Protein |
| Sequence Length | 545 aa |
Luciferin 4-monooxygenase
Review this target as Luciferin 4-monooxygenase, mapped to UniProt Q27757. Sequence length is 545 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL405317 | 7.42 | IC50 | 38.0 | Preclinical |
| CHEMBL460694 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL473735 | 7.27 | IC50 | 54.0 | Preclinical |
| CHEMBL512749 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL472929 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL473126 | 6.5 | IC50 | 320.0 | Preclinical |
| CHEMBL92816 | 6.5 | IC50 | 320.0 | Preclinical |
| CHEMBL460508 | 6.44 | IC50 | 360.0 | Preclinical |
| CHEMBL508666 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL472839 | 6.24 | IC50 | 580.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 34 | 5.6 |
| biochemical format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |