IDO1/von Hippel-Lindau disease tumor suppressor · PROTEIN-PROTEIN INTERACTION · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P14902. Use UniProt P14902 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P14902 as the stable identity anchor, then attach disease evidence before program review.
Indoleamine 2,3-dioxygenase 1
Review this target as IDO1/von Hippel-Lindau disease tumor suppressor, mapped to UniProt P14902. ChEMBL maps the protein component as Indoleamine 2,3-dioxygenase 1. Sequence length is 403 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats IDO1/von Hippel-Lindau disease tumor suppressor as ChEMBL target CHEMBL5169061, mapped to UniProt P14902. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether IDO1/von Hippel-Lindau disease tumor suppressor is the right protein anchor across sources, using UniProt P14902 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | IDO1/von Hippel-Lindau disease tumor suppressor |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P14902 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Indoleamine 2,3-dioxygenase 1 |
| UniProt Accession | P14902 |
| Component Type | Protein |
| Sequence Length | 403 aa |
Indoleamine 2,3-dioxygenase 1
Review this target as IDO1/von Hippel-Lindau disease tumor suppressor, mapped to UniProt P14902. ChEMBL maps the protein component as Indoleamine 2,3-dioxygenase 1. Sequence length is 403 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5192805 | 6.48 | EC50 | 329.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 1 | 6.4 |