Use UniProt Q8WYN0 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5169181 Target Snapshot
Cysteine protease ATG4A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8WYN0. Use UniProt Q8WYN0 as the stable identity anchor, then attach disease evidence before program review.
Cysteine protease ATG4A
Review this target as Cysteine protease ATG4A, mapped to UniProt Q8WYN0. Sequence length is 398 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Cysteine protease ATG4A as ChEMBL target CHEMBL5169181, mapped to UniProt Q8WYN0. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Cysteine protease ATG4A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8WYN0 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cysteine protease ATG4A |
| UniProt Accession | Q8WYN0 |
| Component Type | Protein |
| Sequence Length | 398 aa |
Cysteine protease ATG4A
How to read this target
Review this target as Cysteine protease ATG4A, mapped to UniProt Q8WYN0. Sequence length is 398 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1200438 | 5.89 | IC50 | 1300.0 | Approved |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 5.9 |